Monoclonal antibodies in the treatment of migraine

Monoclonal antibodies in the treatment of migraine
About the method

The most modern and most effective method of migraine treatment today is medication therapy based on antibodies. This method is also called anti-CGRP therapy, because the antibodies that are injected into the human body bind and deactivate the CGRP (calcitonin gene-related peptide) protein.

Research data have shown that during a migraine attack, the nerve endings of the trigeminal nerve release CGRP, which is accompanied by the development of an inflammatory reaction and vasodilation in the meninges. The patient experiences this reaction as a headache, nausea and increased sensitivity to light, sounds or smells. In chronic migraine, when the headache bothers more than half of the days per month, the concentration of CGRP in the nervous system is consistently elevated. If we bind CGRP or its receptor with monoclonal antibodies, we can significantly reduce the number of headache days, the number of migraine attacks, and significantly reduce their severity.

Monoclonal antibody injections for the treatment of migraine appeared in 2018, and one of these drugs (fremanezumab) has been available in Ukraine since July 2020. Our specialists were the first in our country to start prescribing it and since then are the most experienced in using anti-CGRP therapy.

Treatment consists of subcutaneous injections of an antibody medication (fremanezumab) once a month or once every three months, depending on the dose. The procedure is simple and safe and has no serious side effects.

Our specialists can advise you on the need to prescribe anti-CGRP monoclonal antibodies, perform the first injection, and help evaluate its results.

Who is the method recommended for?

Fremanezumab is recommended for the preventive treatment of migraine in adults who have at least 4 attacks per month.

Advantages of the method
  • Proven high efficiency

  • Brevity of the procedure, lack of specific preparing

  • Ability to combine with other methods as part of complex therapy

  • Predicted effect, high safety profile

  • Already after the first procedure, the patient feels relief, which becomes stable after a course of injections

Three main advantages of using monoclonal antibodies in the SPRAVNO medical center
  1. A REALLY comprehensive examination before prescribing the procedure

  2. TRULY qualified specialists with extensive experience in the use of monoclonal antibodies

  3. REALLY high-quality, certified preparations of monoclonal antibodies for the treatment of migraine

Sign up for a consultation!

Our specialists can advise you on the need for anti-CGRP monoclonal antibodies, perform the first injection, and help you evaluate its results.

Reviews
5 / 5
based on
16 reviews
 

We went to the doctor purposefully; we knew about the doctor, our neurosurgeon from Kherson recommended this doctor, and this doctor was also recommended in Kyiv. The doctor met all our requirements, needs, and questions. If necessary, we will definitely reach out again.

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Євген
Verified patient
5

Nice clinic, polite staff at the reception, I was seen on time, the appointment with the neurologist lasted an hour, there was time to discuss all questions, the doctor prescribed treatment, the treatment is ongoing, I am waiting for the results of the treatment, I had no complaints about the doctor.

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М
Марина
Verified patient
5

The doctor listened carefully to my complaints, recommended which procedures to undergo and which medications to take, I enjoyed communicating with her, she explained everything in an accessible way about what needed to be done.

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Я
Ярослав
Verified patient
5

Everything was great, no problems. Thank you very much.

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Ю
Юлия
Verified patient
5

I liked the doctor as a person and as a specialist. She explained everything clearly and directly, prescribed tests. I am very satisfied with the visit and liked the quality of service.

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В
Вікторія
Verified patient
5

I recommend, a very good doctor! It is clear that the doctor is educated, understands everything, was able to partially solve our problem, does not impose anything unnecessary, devoted enough time to us, we were satisfied with the doctor.

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Ю
Юлія
Verified patient
5

I really liked the doctor, good attitude, attentive. He clearly assigns everything according to the diagnosis, nothing unnecessary. We are very satisfied with the appointment.

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Н
Наталя
Verified patient
5

I am satisfied with the consultation with Dr. Beloshitsky Vadim Vasilievich. A attentive doctor who gives proper attention to patients.

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И
Ирина
Verified patient
5

Very satisfied. Additional examination and treatment were prescribed.

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Н
Наталья
Verified patient
5

The doctor was very likable as a person and as a specialist, very caring and attentive. I left satisfied.

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О
Олег
Verified patient
5

He listened to me, clarified all the issues, diagnosed, said we will fight the problem, and we will find out what other issues may exist in the process.

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Д
Дмитрий
Verified patient
5

I was satisfied with the appointment, the doctor is competent and explained everything in detail. I recommend!

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Наталья
Verified patient
5
4.7 / 5
based on
102 reviews
 

An excellent clinic that specializes in the treatment of chronic pain. A professional approach, modern equipment, and attentive staff create a comfortable environment for patients. The treatment results exceed expectations – the pain has significantly decreased, and the quality of life has improved. I recommend it to anyone looking for effective help in dealing with pain.

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В
Валерій
Verified patient
5
Google Reviews
Good day, I want to thank Dr. Vadim Vasilyevich for his help with my rare disease, Blepharospasm + Orofacial Dystonia. They administered 100 units of Xeomin, and by the third day, I started to feel changes; my eyes opened up, the tension in my jaw muscles and chin was relieved, and I began to eat normally. Before the procedure, I couldn’t eat as everything was tight. Therefore, I recommend this clinic and Dr. Vadim Vasilyevich, who listened attentively and helped me.
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Галина
Verified patient
5

Hello, my mother has had headaches (migraine) for over 20 years, and it got to the point where she was taking painkillers several times a day, leading to dependence and the feeling that nothing would help. However, after consulting many doctors and spending a lot of time and money, her condition only worsened because they were treating something entirely different, which only caused side effects. We decided to try the drug Azhovi, or rather botulinum toxin. We chose the SPRAVNO Pain Medicine Center because of their democratic prices, direct supplies, and confirmation of the quality and originality of the drug. Most importantly, the professionalism of Vadym Vasylovych Biloshytskyi, who established the correct diagnosis and prescribed treatment with Azhovi. The treatment is still ongoing, but already from the start, 80% of the pain has disappeared, the quality of life has changed, blood pressure has normalized, and muscle tone has improved.

I sincerely thank the doctor and the SPRAVNO staff! I recommend it.

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Д
Доріан
Verified patient
5

For about 10 years, I have been suffering from migraines and tension headaches. The pain has become daily and unbearable over time. During the day, I could take 4-5 painkillers; some helped, some no longer did. I consulted various neurologists, who prescribed triptans and simply advised me to get pregnant, saying “the migraine might go away.”
I had already given up on the idea that someone could help me and was just relying on painkillers. Over time, I realized that it was impossible to live my whole life taking painkillers, as they were causing headaches too, and I started looking for a solution again.
I found the Spravno clinic, made an appointment for a consultation with Marina Vadymivna Biloshytska, and since then my life has been divided into before and after! I am happy to write this))
I have been undergoing treatment for half a year and have wonderful results; I haven’t taken painkillers for over a month now—this is already a small victory..!))
Marina Vadymivna is a fantastic professional, an excellent doctor, caring and attentive! In my years, I have rarely met such sincere and caring doctors; Marina Vadymivna is just like that.) She found an approach to my body, supported me through all stages of treatment, never left me with questions in my head, and selected a medication purely based on individual indicators..!
I am very grateful to the clinic; the administrator is always friendly and has connected me with the doctor whenever needed.
Marina Vadymivna Biloshytska is a neurologist whom I recommend from the bottom of my heart!

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Е
Емма
Verified patient
5

I want to express my immense gratitude to this clinic, especially to doctor Biloshytska M. V. Patients are treated here as unique individual cases, not just another conveyor belt patient, whose illness (and everything related to it) is not delved into. Attention to detail, masterful work (I go for botulinum toxin injections), and always a caring attitude. Of course, there is little joy when you have something that brought you to a pain medicine clinic, but it is pleasant to return here.

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Є
Євгенія
Verified patient
5

Thank you, Ruslan Yevheniyovych, for your help! A wonderful doctor, very attentive and knows his stuff.

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Людмила
Verified patient
5

Good afternoon, underwent a procedure for treating the trigeminal nerve at the center, very pleased with the staff, the facilities and the attentive care. Special thanks to Vadim Vasilievich. I highly recommend this center for examinations and procedures, very grateful

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Н
Наталья
Verified patient
5
Google Reviews
I really liked the clinic, pleasant and competent doctors, polite administrator.
I have already been to see Dr. Biloshytska M.V. several times, and the doctor helped me get out of the critical condition I was in. Thank you very much for the help and treatment!
I recommend the SPRAVNO clinic and especially Dr. Biloshytska M.V. as a great specialist, as she helped me a lot.
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С
Світлана
Verified patient
5

I want to express my immense gratitude to the professionals in their field: neurosurgeon Vadim Vasilievich Biloshytsky and neurologist Marina Vadimivna Biloshytska, as well as the “SPRAVNO” clinic for their responsible and conscientious attitude towards their work and patients, for their high qualifications, and for their help in solving the problem. We succeeded!
I highly recommend them!!

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С
Сергій
Verified patient
5

Sincere recommendations
Doctor Inna Buvallo identified the cause of the pain and resolved it in one procedure

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Т
Теа
Verified patient
5

For about 8-9 years, I was looking for the cause of my headaches and was treated by various doctors. At the pain management center, SPRAVNO, Marina Vadimivna Biloshytska diagnosed me, prescribed treatment, and within two weeks, there was a positive result, for which I am very grateful to Marina Vadimivna.
I recommend it to everyone, a very good clinic.

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М
Михайло
Verified patient
5

I had a consultation with neurologist Buvailo I.V., a highly competent and attentive doctor. I received answers to all my questions and we developed a treatment plan.

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Л
Леся
Verified patient
5
The information on this website is for informational purposes only and does not constitute medical advice.
Diagnosis and treatment decisions should be made by a qualified healthcare professional after a personal consultation. Do not engage in self-medication.
Maria · Consulting doctor
Maria · Consulting doctor
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